SISTEMA LC/MS AGILENT serie 1290 INFINITY II/6495MSD a triplo quadrupolo con autocampionatore
Sapienza Università di Roma
The system is a liquid ultra-chromatography coupled with tandem mass spectrometry (UHPLC-MS / MS). Chromatography is equipped with a high-pressure binary pumping module and double-needle autosampler. The spectrometer is a triple quadrupole (QQQ) tandem mass analyzer with an ESI ion source.
LS4_4 - Endocrinology - Physiology in Health, Disease and Ageing
LS7_11 - Environmental health, occupational medicine - Prevention, Diagnosis and Treatment of Human Diseases
Metabolomics
Metabolism
Sex steroid hormones
Environmental pollution
Open Access with fees for use. Project must be pre-approved by Lab Commetee of the Department of Experimental Medicine. Fess are posted on the Dept web-sites.
AGILENT INFINITY 1290 II / LC-MS / MS is extensively applied for the trace analysis of organic substances of pharmaco-toxicological interest in complex matrices (environmental and agri-food matrices, pharmaceutical and nutraceutical products, fluids and biological tissues). In areas of biomedical interest, LC-MS / MS can be used for the determination in biological fluids of steroid and peptide hormones and / or substances capable of altering their levels (e.g. endocrine disruptors), for therapeutic monitoring, for study of the metabolism of new active ingredients, for the analysis of new drugs of abuse in biological and non-biological matrices.