Chiral Chromatography and Dynamic Stereochemistry platform

OVERVIEW
Acronym CCSD-PTA
Partner institution

Aix-Marseille Université





Description

CCSD gathers equipments and the know-how to separate racemic mixtures at analytical and preparative scales by chromatography, as well as how to characterize enantiomers (based on chiroptical properties, absolute configuration, and racemization barrier).

SCIENTIFIC DOMAIN
Scientific domain

PE5_11 - Biological chemistry and chemical biology - Synthetic Chemistry and Materials





 

PE5_1 - Structural properties of materials - Synthetic Chemistry and Materials





Keywords

Chirality





 

enantiomers





 

stereochemistry





 

chiroptical





 

racemization





INFRASTRUCTURE
Remote access details

CCSD services can be provided to both the academic and private sectors; the modalities for request though differ.

AMENITIES
Equipment

Among the services provided by CCSD are: 

  • the development of analytical methods to separate racemic mixtures on chiral stationary phases, 
  • measurement of enantiomeric excesses, 
  • preparative separation by chiral chromatography to obtain enantiomers from milligram to gram scale, 
  • determination of enantiomerization barriers, 
  • measurement of chiroptical properties : polarimetry and circular dichroism.