Antiviral Drug Design Platform
Coordinates
43.29236346203756, 5.359133426541125
Contact name
Jean-Claude Guillemot
CIVIS Label
No
Acronym
AD2P-PTA
Scientific domain
LS1_11 - Chemical biology - Molecules of Life: Biological Mechanisms, Structures and Functions
LS7_9 - Public health and epidemiology - Prevention, Diagnosis and Treatment of Human Diseases
LS6_6 - Infectious diseases - Immunity, Infection and Immunotherapy
LS8_4 - Population biology, population dynamics, population genetics - Environmental Biology, Ecology and Evolution
LS9_2 - Applied genetics, gene editing and transgenic organisms - Biotechnology and Biosystems Engineering
Keywords
HTS
Antivirals
Emerging Viruses
2P2I
Partner institution
Aix-Marseille Université
Website
No
Technical staff available
No
Remote access details
AD2P is accessible to scientific communities of both the academic and private sectors, upon request.
Remote access available
No
Open to external users
No
Equipment
Here below are examples of the services ADP2 can provide:
-screening of antivirals against emerging viruses e.g., Dengue, Zika , WNV, Chik , VEEV, SARS, MERS, TBE, JEV,
-screening against clinical virus isolates-development of new antiviral strategies e.g., HTRF, 2P2I,
-structure based drug design,
-cheminformatics, and creation of chemolibraries,
-Hit to Lead optimisation
Open access to updated information database
No
Online booking system details
Charte des Plateformes Technologiques Aix-Marseille (PTA): https://www.univ-amu.fr/system/files/2021-07/Charte%20PTF%20AMU%20M%C3%A0J21.docx.pdf
Online booking system available
No
Description
AD2P (also locally refered as 'Plateforme de Criblage Marseille-Luminy = PCML) plays a significant role in the research field of antivirals against emerging viruses. Indeed, the facility has developed and offers expertise in the screening of viral enzyme inhibitors, protein/protein interactions, clinical virus isolates, the supply of chemical libraries, as well as in the development of new technologies and drug design.