Drug Design and Discovery

The virtual program will consist of online lectures and seminaries organized throughout the spring/summer semester 2024 twice per week for eight weeks. The lectures will be held in a synchronous fashion via Zoom, Cisco/Webex, Teams or similar tools. Based on the complex nature of in term learning and participation duties of students across multiple courses of studies, years and universities in different countries, the lectures will be recorded and provided additionally as a video in a timely manner within the CIVIS moodle course. Thus, students missing (parts of) the lecture can, watch the video at any time. In order to ensure that the participation of all students is checked and documented, multiple choice-based quizzes will be implemented in Moodle for each lecture, which need to be passed with at least 50% of the full points possible within a few weeks after the lecture. A detailed schedule of the virtual part (planned program as of 4th Sept. 2023) can be found in the attached pdf document. "Drug Design and Discovery: Hot Topics, Tools, Technologies, and Translation @ Tübingen" (D3HT5) is a multidisciplinary program, focused on the understanding of the interactions between pharmacologically interesting targets and small molecules and its plurality of manifestations in the drug discovery and development value chain, using a broad diversity of experimental and computational methods or approaches, including analytical, biological, biochemical, biophysical, cellular, chemical, informatics-based, structural, or theoretical.

Application Deadline

Virtual Part starting date 2024-04-30

Virtual Part closing date 2024-06-21

Total student workload 180

Specific field of studies Pharmacy, Pharmaceutical Sciences, Chemistry, Biochemistry, Biophysics, Medicine, Medical Sciences, Biology, Bioinformatics, ... (please ensure that ECTS points can be credited to your course of studies!)

Pre-requisite for selection CV Motivation Letter

Academic pre-requisites for applicants Applicants should have a strong background in pharmaceutical, natural and/or biomedical sciences.

Physical Part starting date 2024-07-22

Physical Part Description The physical component of the program will consist of an one week summer school in which the students will participate in lectures, seminaries, hands-on-courses and practical tutorials covering the following topics: · New strategies to develop drugs for neurodegenerative diseases / Methods to measure calcium - Tools for drug discovery - Prof. Maria F. Cano Abad, Facultad de Medicina, Universitad Autónoma Madrid · Microbicidal versus antipathogenic strategies in antimicrobial drug discovery - Prof. Dr. Carmen Chifiriuc, University of Bucharest · Introduction to physiologically-based modelling - Prof. Florence Gattacceca, Faculty of Pharmacy, Aix-Marseille Université · Methods for the In vitro Assessment of Antimicrobial Activity - Prof. Dr. Luminita Marutescu, Faculty of Biology, University of Bucharest · NMR-based Metabolomics - Prof. Emmanuel Mikros, Faculty of Pharmacy, National Kapodistrian University of Athens · Practical Aspects in Building (3D-) QSAR Models and their Validation - Prof. Rino Ragno, Faculty of Pharmacy, La Sapienza University Rome · The Versatility of Halogen Bonding / Methods in CompChem - Choose wisely and apply with care! - Prof. Frank M. Böckler, Dept. of Pharmacy and Biochemistry, Faculty of Science, Eberhard Karls Universität Tübingen · Applied Bioanalytics - Prof. Michael Lämmerhofer, Dept. of Pharmacy and Biochemistry, Faculty of Science, Eberhard Karls Universität Tübingen · Direct Powder Extrusion 3D-printing: Challenges and Opportunities - Prof. Dominique Lunter, Dept. of Pharmacy and Biochemistry, Faculty of Science, Eberhard Karls Universität Tübingen · Principles and Applications of Chalcogen Bonding / Introduction Hands-on-Course: CompChem / VS / ML - Dr. Markus O. Zimmermann, Dept. of Pharmacy and Biochemistry, Faculty of Science, Eberhard Karls Universität Tübingen · Gastroplus ADMET Predictor to Screen Gastro-intestinal Absorption and Metabolism Properties - Prof. Florence Gattacceca, Faculty of Pharmacy, Aix-Marseille Université · 3D QSAR Practical Course - Prof. Rino Ragno, Faculty of Pharmacy, La Sapienza University Rome · Hands-on-Course: Computational Chemistry / Virtual Screening / Machine Learning - Dr. Markus O. Zimmermann, Dept. of Pharmacy and Biochemistry, Faculty of Science, Eberhard Karls Universität Tübingen · Hands-on-Molecular-Biophysics ( Differential Scanning Fluorimetry / Isothermal Titriation Calorimetry / Fluorescence Polarization / Crystallography ) - Prof. Frank M. Böckler, Dept. of Pharmacy and Biochemistry, Faculty of Science, Eberhard Karls Universität Tübingen · Patent Writing and Application Seminary - Dr. M. Bergauer, AMGEN, Los Angeles, USA

Physical Part closing date 2024-07-26

Language level required Not-applicable

Field of studies related to the course Medicine and Health Computer Science and IT Natural Sciences and Mathematics

Course location Tübingen, Germany

Course language English