UniReM supports cutting-edge research in chemistry, physics, biology and related fields, in order to contribute to achievement of highly qualified human resources. UniReM represents an operational, single-sited, regional and open-access research infrastructure that supports fundamental research activities in fields like organic chemisry, inorganic chemistry, physics, materials sciences etc. UniReM holds two spectrometers that operate at proton Larmor frequences of 500 MHz and 300 MHz (in magnetic fields B0 = 11.75 T and B0 = 7.05 T, respectively), both equipped with autosamplers. The main applications of UniReM include: i) synthetic small-molecules structural confirmation, ii) protein structural determinations, protein-ligand interaction studies, eznyme transformations; iii) metabolomics on cell cultures and samples provided by medical units interested to use the facility for clinical research. Nuclear magnetic resonance (NMR) instrument allows the molecular structure of a material to be analyzed by observing and measuring the interaction of nuclear spins when placed in a powerful magnetic field. The advantages of NMR are that sample measurements are non-destructive and there is less sample preparation required. UniReM holds two spectrometers: 300 MHz Bruker Fourier NMR spectrometer • operating at 6.9 T, corresponding to the resonance frequency of 300.18 MHz for the 1H nucleus. • automated instrument, on-flow NMR sample analysis by running IconNMR under Bruker TOPSPIN 3.2 for structure elucidation of liquid samples. • autosampler - 16 positions. • 5 mm indirect observation z-gradient inverse a dual proton/carbon probe (1H/13C) - BBI probe 500 MHz Bruker Advance Ultrashield Plus NMR spectrometer • operating at 11.74 T, corresponding to the resonance frequency of 500.13 MHz for the 1H nucleus. • automated instrument, on-flow NMR sample analysis by running IconNMR under Bruker TOPSPIN 3.2 for structure elucidation of liquid samples. • autosampler - 16 positions. • two probes are available on the solution 500MHz NMR: 5 mm indirect observation z-gradient inverse (1H/13C) - BBI probe (BB / 1H / 2H Channels; X-nuclei direct detection) and 5 mm z-gradient direct observation (1H/13C/19F)- BBFO probe (BB / 1H / 2H Channels; X-nuclei direct detection).